Manchester United - Dynamo Kiev
Ferguson had ear-marked this game for club captain Gary Neville’s comeback, but the defender’s setback has now ruled him out, making him the manager's only fresh injury concern.
Striker Louis Saha could come into contention, while midfielder Owen Hargreaves is primed to make his European debut for United.
The visitors will have to contend with the absence of Maksim Shatskikh and Valentin Belkevich. However the return of fit-again Sergei Rebrov and the maturity of blossoming defender Oleh Dopilka gives Kiev a much-needed boost.2-0/3-0/4-1 (6.20/5.50/11.00)
LS: AOS (10.00)
FC Barcelona - Rangers
Rijkaard's main doubt is over the fitness over Gianluca Zambrotta. If the Italian does not make it then Carles Puyol could move across to the right of the defence with Lilian Thuram or Rafa Márquez coming into the centre. Alternatively, Oleguer could slot straight in leave Puyol in the middle. Touré Yaya, Xavi and Andrés Iniesta will be the three midfielders, while Leo Messi, Ronaldinho and Thierry Henry will up front.
Kevin Thomson is suspended, but otherwise Smith has a full squad to choose from. Brahim Hemdani, Jean-Claude Darcheville and Charlie Adam are all available after returning to action recently so it is down to the manager to see how many changes he wants to make. Smith is set to rotate his players, but not change the team's system from the first match.
2-0 (5.80)
LS: DRAW (5.15)
Inter Milan - CSKA Moscow
Coach Roberto Mancini will be worried about the series of injuries that have hit the team recently particularly in midfield, Luis Figo being the last casualty as he suffered a fracture during the ‘Derby d’Italia’ after a clash with Pavel Nedved. Patrick Vieira is out until next year, while Dejan Stankovic recently suffered a calf injury that will keep him out for about a month.
Russian visitors to the San Siro is boosted by the return of Igor Akinfeev, Aleksei Berezutski and Vágner Love, who could partner Jô up front. Akinfeev and Berezutski were both in action on Saturday as CSKA beat FC Kuban Krasnodar 1-0 to move up to third in the Russian standings.
+1.5 (1.85)
Slavia Prague-Arsenal
Ladislav Volešák will have to serve a one-match suspension, having picked up yellow cards in each of Slavia's first three games.
Four Slavia players have appeared in all seven of the club's Champions League games so far this season: Martin Vaniak, Marek Suchý, Matej Krajcík and Stanislav Vlcek.
But striker Vlcek faces at least two weeks out through injury, while Petr Janda underwent knee surgery last Wednesday and will be sidelined until after the winter break.
Cesc Fabregas, Kolo Toure, Tomas Rosicky and Alexander Hleb have all stayed in London. Theo Walcott and Eduardo are vying to start alongside Emmanuel Adebayor in attack.
+1.5 (1.53)
LS: 0-1 (6.50)
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